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Opioid Receptors Inhibit the Spinal AMPA Receptor Ca(2+) Permeability that Mediates Latent Pain Sensitization

Acute inflammation induces sensitization of nociceptive neurons and triggers the accumulation of calcium permeable (CP) α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) in the dorsal horn of the spinal cord. This coincides with behavioral signs of acute inflammatory pain, but...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Neurol
Prif Awduron: Taylor, Bradley K., Sinha, Ghanshyam P., Donahue, Renee R., Grachen, Carolyn M., Morón, Jose A., Doolen, Suzanne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559354/
https://ncbi.nlm.nih.gov/pubmed/30660616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.01.003
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