EGFR is required for Wnt9a/Fzd9b signalling specificity in haematopoietic stem cells

Wnt signalling drives a plethora of processes in development, homeostasis, and disease; however, the role and mechanism of individual ligand/receptor (Wnt/Frizzled, Fzd) interactions in specific biological processes remain poorly understood. Wnt9a is specifically required for the amplification of bl...

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Pubblicato in:Nat Cell Biol
Autori principali: Grainger, Stephanie, Nguyen, Nicole, Richter, Jenna, Setayesh, Jordan, Lonquich, Brianna, Oon, Chet Huan, Wozniak, Jacob M., Barahona, Rocio, Kamei, Caramai N., Houston, Jack, Carrillo-Terrazas, Marvic, Drummond, Iain A., Gonzalez, David, Willert, Karl, Traver, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559346/
https://ncbi.nlm.nih.gov/pubmed/31110287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0330-5
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