A Phase I, Randomized, Controlled Clinical Study of CC-11050 in People Living With HIV With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE)

OBJECTIVE: Phosphodiesterase 4 inhibitors (PDE4i) are novel anti-inflammatory medications that have been approved for rheumatologic diseases and have been tested as host-directed therapy in tuberculosis. We examined the safety of CC-11050, a potent PDE4i in people living with HIV (PLWH) with suppres...

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Dettagli Bibliografici
Pubblicato in:Open Forum Infect Dis
Autori principali: Boulougoura, Afroditi, Gabriel, Erin, Laidlaw, Elizabeth, Khetani, Vikram, Arakawa, Ken, Higgins, Jeanette, Rupert, Adam, Gorelick, Robert J, Lumbard, Keith, Pau, Alice, Poole, April, Kibiy, Angela, Kumar, Princy, Sereti, Irini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Editor's Choice
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559277/
https://ncbi.nlm.nih.gov/pubmed/31211164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz246
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