Neuronal Lamin regulates motor circuit integrity and controls motor function and lifespan

Neuronal aging involves a progressive decline in cognitive abilities and loss of motor function. Mutations in human Lamin genes (LMNA, LMNB1, LMNB2) lead to a wide-range of diseases including muscular dystrophy, peripheral neuropathy and progeria. Here we investigate the role of neuronal Lamin in re...

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Vydáno v:Cell Stress
Hlavní autoři: Oyston, Lisa J., Lin, Yong Qi, Khuong, Thang M., Wang, Qiao-Ping, Lau, Man Tat, Clark, Teleri, Neely, G. Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: Shared Science Publishers OG 2018
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558924/
https://ncbi.nlm.nih.gov/pubmed/31225490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.09.152
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