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Protein-protein interaction prediction using a hybrid feature representation and a stacked generalization scheme

BACKGROUND: Although various machine learning-based predictors have been developed for estimating protein–protein interactions, their performances vary with dataset and species, and are affected by two primary aspects: choice of learning algorithm, and the representation of protein pairs. To improve...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Chen, Kuan-Hsi, Wang, Tsai-Feng, Hu, Yuh-Jyh
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558856/
https://ncbi.nlm.nih.gov/pubmed/31182027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2907-1
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