Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies

BACKGROUND: In Genome-Wide Association Studies (GWAS), the concept of linkage disequilibrium is important as it allows identifying genetic markers that tag the actual causal variants. In Genome-Wide Association Interaction Studies (GWAIS), similar principles hold for pairs of causal variants. Howeve...

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Detalles Bibliográficos
Publicado en:BioData Min
Autores principales: Joiret, Marc, Mahachie John, Jestinah M., Gusareva, Elena S., Van Steen, Kristel
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558841/
https://ncbi.nlm.nih.gov/pubmed/31198442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-019-0199-7
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