The safety and tolerability of combined immune checkpoint inhibitors (anti-PD-1/PD-L1 plus anti-CTLA-4): a systematic review and meta-analysis

BACKGROUND: The future of combined immunotherapy (a PD-1/PD-L1 plus a CTLA-4 antagonist) is very bright. However, besides improving efficacy, combined therapy increases treatment-related adverse events (TRAEs). Also, the clinical application is limited in some solid tumors. METHODS: This paper purpo...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gu, Lihu, Khadaroo, Parikshit Asutosh, Su, Hui, Kong, Liya, Chen, Liangliang, Wang, Xianfa, Li, Xinlong, Zhu, Hepan, Zhong, Xin, Pan, Junhai, Chen, Manman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558837/
https://ncbi.nlm.nih.gov/pubmed/31182049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5785-z
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