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MicroRNA-198 inhibits proliferation and induces apoptosis by directly suppressing FGFR1 in gastric cancer

MicroRNAs (miRNAs) are increasingly recognized as important therapeutic targets in cancer. Here we aim to investigate the role of miR-198, a broad-spectrum tumor suppressor, in gastric cancer (GC). MiR-198 overexpression was achieved by transfection of miR-198 mimics, followed by evaluation of cell...

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Détails bibliographiques
Publié dans:Biosci Rep
Auteurs principaux: Gu, Junxia, Li, Xiaozhen, Li, Hui, Jin, Zhe, Jin, Jianjun
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558723/
https://ncbi.nlm.nih.gov/pubmed/31138759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181258
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