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Optimizing checkpoint inhibitors therapy for relapsed or progressive classic Hodgkin lymphoma by multiplex immunohistochemistry of the tumor microenvironment

Immune checkpoint‐blocking antibodies have therapeutic activity against relapsed or progressive classic Hodgkin lymphoma (cHL), but Hodgkin Reed‐Sternberg cells can develop resistance to this therapy via multiple mechanisms. To improve the efficacy of immune checkpoint blockade, we need a more preci...

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Détails bibliographiques
Publié dans:Cancer Med
Auteurs principaux: Carbone, Antonino, Gloghini, Annunziata, Pruneri, Giancarlo, Dolcetti, Riccardo
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558469/
https://ncbi.nlm.nih.gov/pubmed/31070022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2168
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