Systematic evaluation of cancer‐specific genetic risk score for 11 types of cancer in The Cancer Genome Atlas and Electronic Medical Records and Genomics cohorts

BACKGROUND: Genetic risk score (GRS) is an odds ratio (OR)‐weighted and population‐standardized method for measuring cumulative effect of multiple risk‐associated single nucleotide polymorphisms (SNPs). We hypothesize that GRS is a valid tool for risk assessment of most common cancers. METHODS: Util...

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Udgivet i:Cancer Med
Main Authors: Shi, Zhuqing, Yu, Hongjie, Wu, Yishuo, Lin, Xiaoling, Bao, Quanwa, Jia, Haifei, Perschon, Chelsea, Duggan, David, Helfand, Brian T., Zheng, Siqun L., Xu, Jianfeng
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Cancer Prevention
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558466/
https://ncbi.nlm.nih.gov/pubmed/30968590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2143
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