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Increased CD14(+)HLA-DR(−/low) Myeloid-Derived Suppressor Cells Correlate With Disease Severity in Systemic Lupus Erythematosus Patients in an iNOS-Dependent Manner

Myeloid-derived suppressor cells (MDSCs) comprise of a population of cells, which suppress the innate and adaptive immune system via different mechanisms. MDSCs are accumulated under pathological conditions. The present study aimed to clarify the pathological role of MDSCs in systemic lupus erythema...

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Publicat a:Front Immunol
Autors principals: Wang, Zhitao, Zhu, Fengfeng, Wang, Jiyu, Tao, Qianshan, Xu, Xuanxuan, Wang, Huiping, Xiong, Shudao, Wang, Yiping, Zhai, Zhimin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558381/
https://ncbi.nlm.nih.gov/pubmed/31231374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01202
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