Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles

Gastrointestinal toxicity is a frequently observed adverse event during cancer treatment with traditional chemotherapeutics. Currently, traditional chemotherapeutics are often combined with targeted biologic agents. These biologics, however, possess a distinct toxicity profile, and they may also exa...

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Vydáno v:Transl Oncol
Hlavní autoři: Forsgård, Richard A., Marrachelli, Vannina G, Lindén, Jere, Frias, Rafael, Collado, Maria Carmen, Korpela, Riitta, Monleon, Daniel, Spillmann, Thomas, Österlund, Pia
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2019
Témata:
Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558216/
https://ncbi.nlm.nih.gov/pubmed/31176994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.04.019
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