Circulating Relaxin-1 Level Is a Surrogate Marker of Myocardial Fibrosis in HFrEF

Introduction: Relaxin-1 (RLN1) has emerged as a possible therapeutic target in myocardial fibrosis due to its anti-fibrotic effects. Previous randomized clinical trials investigated therapeutic role of exogenous relaxin in patients with acute-on-chronic heart failure (HF) and failed to meet clinical...

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Detalles Bibliográficos
Publicado en:Front Physiol
Autores principales: Simon, Judit, Nemeth, Endre, Nemes, Annamaria, Husveth-Toth, Maria, Radovits, Tamas, Foldes, Gabor, Kiss, Loretta, Bagyura, Zsolt, Skopal, Judit, Merkely, Bela, Gara, Edit
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558211/
https://ncbi.nlm.nih.gov/pubmed/31231242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00690
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