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Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis

Glucosamine (GlcN) and its acetylated derivative N-acetylglucosamine (GlcNAc) are widely used in the pharmaceutical industries. Here, we attempted to achieve efficient production of GlcNAc via genomic engineering of Corynebacterium glutamicum. Specifically, we ligated the GNA1 gene, which converts G...

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Detalhes bibliográficos
Publicado no:Synth Syst Biotechnol
Main Authors: Deng, Chen, Lv, Xueqin, Liu, Yanfeng, Li, Jianghua, Lu, Wei, Du, Guocheng, Liu, Long
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558094/
https://ncbi.nlm.nih.gov/pubmed/31198861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2019.05.002
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