Discovery of Potential Anti-infective Therapy Targeting Glutamine Synthetase in Staphylococcus xylosus

Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential roles in most biological growth and biofilm formation, suggesting that GS may be used as a promising target for antibacterial therapy. We asked whether a GS inhibitor could be found as an anti-infective agent of...

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Bibliografske podrobnosti
izdano v:Front Chem
Main Authors: Cui, Wen-Qiang, Qu, Qian-Wei, Wang, Jin-Peng, Bai, Jing-Wen, Bello-Onaghise, God'spower, Li, Yu-Ang, Zhou, Yong-Hui, Chen, Xing-Ru, Liu, Xin, Zheng, Si-Di, Xing, Xiao-Xu, Eliphaz, Nsabimana, Li, Yan-Hua
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558069/
https://ncbi.nlm.nih.gov/pubmed/31214565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00381
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