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Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?

Fc fusion proteins and Fc fusion peptides or peptibodies are chimeric molecules composed of an active pharmacological protein or peptide and the Fc fragment of an immunoglobulin. The primary aim of this drug construct is to prolong the half-life of the active component. This molecular architecture i...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Schifferli, Alexandra, Nimmerjahn, Falk, Kühne, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557984/
https://ncbi.nlm.nih.gov/pubmed/31214173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01196
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