Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1

BACKGROUND: Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4(+) T cells within those who are infected. Finding a safe and effective means to induce latency reversal (LR) during ART to specifically expose this late...

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發表在:EBioMedicine
Main Authors: Kristoff, Jan, Palma, Mariana L., Garcia-Bates, Tatiana M., Shen, Chengli, Sluis-Cremer, Nicolas, Gupta, Phalguni, Rinaldo, Charles R., Mailliard, Robbie B.
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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Research paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557749/
https://ncbi.nlm.nih.gov/pubmed/30952614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.077
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