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Trefoil factor family: unresolved questions and clinical perspectives

The three trefoil factor family peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. Major gaps in understanding their molecular function have however hampered therapeutic development for gastrointestinal disorders. Here, we provide a critic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Trends Biochem Sci
Hauptverfasser: Braga Emidio, Nayara, Hoffmann, Werner, Brierley, Stuart M., Muttenthaler, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557713/
https://ncbi.nlm.nih.gov/pubmed/30792027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2019.01.004
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