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Regulation of Interleukin-1 beta secretion from Macrophages via modulation of Potassium ion (K(+)) channel activity
A causal relationship exists between macrophage cholesterol levels and inflammation, e.g., Interleukin-1β (IL-1β) secretion. A decrease in intracellular K(+) is essential for inflammasome activation/IL-1β secretion and, herein, we examined the hypothesis that cellular cholesterol affects K(+)-channe...
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| Gepubliceerd in: | FEBS Lett |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557664/ https://ncbi.nlm.nih.gov/pubmed/31026357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13395 |
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