Fimbriae reprogram host gene expression – Divergent effects of P and type 1 fimbriae

Pathogens rely on a complex virulence gene repertoire to successfully attack their hosts. We were therefore surprised to find that a single fimbrial gene reconstitution can return the virulence-attenuated commensal strain Escherichia coli 83972 to virulence, defined by a disease phenotype in human h...

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Vydáno v:PLoS Pathog
Hlavní autoři: Ambite, Ines, Butler, Daniel S. C., Stork, Christoph, Grönberg-Hernández, Jenny, Köves, Bela, Zdziarski, Jaroslaw, Pinkner, Jerome, Hultgren, Scott J., Dobrindt, Ulrich, Wullt, Björn, Svanborg, Catharina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557620/
https://ncbi.nlm.nih.gov/pubmed/31181116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007671
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