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Hormone therapy use and breast tissue DNA methylation: analysis of epigenome wide data from the normal breast study

Hormone therapy (HT) is associated with increased risk of breast cancer, strongly dependent on type, duration, and recency of use. HT use could affect cancer risk by changing breast tissue transcriptional programs. We hypothesize that these changes are preceded by changes in DNA methylation. To expl...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Harlid, Sophia, Xu, Zongli, Kirk, Erin, Wilson, Lauren E., Troester, Melissa A., Taylor, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557608/
https://ncbi.nlm.nih.gov/pubmed/30821641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1580111
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