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Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis

An ancient enzyme family responsible for the catabolism of the prebiotic chemical cyanuric acid (1,3,5-triazine-2,4,6-triol) was recently discovered and is undergoing proliferation in the modern world due to industrial synthesis and dissemination of 1,3,5-triazine compounds. Cyanuric acid has a high...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shi, Ke, Cho, Seunghee, Aukema, Kelly G., Lee, Thomas, Bera, Asim K., Seffernick, Jennifer L., Wackett, Lawrence P., Aihara, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557486/
https://ncbi.nlm.nih.gov/pubmed/31181074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216979
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