Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome

BACKGROUND: Hypereosinophilic syndrome is a group of diseases defined by marked eosinophilia in blood or tissue and eosinophil-related clinical manifestations. Benralizumab is a monoclonal antibody against interleukin-5 receptor α, which is expressed on human eosinophils. METHODS: In this randomized...

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Udgivet i:N Engl J Med
Main Authors: Kuang, Fei Li, Legrand, Fanny, Makiya, Michelle, Ware, JeanAnne, Wetzler, Lauren, Brown, Thomas, Magee, Tamika, Piligian, Brent, Yoon, Pryscilla, Ellis, Jamie H., Sun, Xiaoping, Panch, Sandhya R., Powers, Astin, Alao, Hawwa, Kumar, Sheila, Quezado, Martha, Yan, Li, Lee, Nancy, Kolbeck, Roland, Newbold, Paul, Goldman, Mitchell, Fay, Michael P., Khoury, Paneez, Maric, Irina, Klion, Amy D.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557265/
https://ncbi.nlm.nih.gov/pubmed/30943337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1812185
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