Development, validation, and comparison of gene analysis methods for detecting EGFR mutation from non-small cell lung cancer patients-derived circulating free DNA

The feasibility and required sensitivity of circulating free DNA (cfDNA)-based detection methods in second-line epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment are not well elucidated. We examined T790M and other activating mutations of EGFR by cfDNA to assess the cli...

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Pubblicato in:Oncotarget
Autori principali: Hanibuchi, Masaki, Kanoh, Akira, Kuramoto, Takuya, Saito, Tatsuro, Tobiume, Makoto, Saijo, Atsuro, Kozai, Hiroyuki, Kondo, Mayo, Morizumi, Shun, Yoneda, Hiroto, Kagawa, Kozo, Ogino, Hirokazu, Sato, Seidai, Kawano, Hiroshi, Otsuka, Kenji, Toyoda, Yuko, Nokihara, Hiroshi, Goto, Hisatsugu, Nishioka, Yasuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557207/
https://ncbi.nlm.nih.gov/pubmed/31217900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26951
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