No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial

Background: Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity. The WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women with PPH. To determine whether TXA has pro-thrombotic effects in women with PPH, we measured endogenous thrombin po...

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Udgivet i:Wellcome Open Res
Main Authors: Dallaku, Kastriot, Shakur-Still, Haleema, Beaumont, Danielle, Roberts, Ian, Huque, Sumaya, Delius, Maria, Holdenrieder, Stefan, Gliozheni, Orion, Mansmann, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556984/
https://ncbi.nlm.nih.gov/pubmed/31223662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14977.1
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