Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer

The AURORA pathway participates in mitosis and cell division, and alterations in mitosis and cell division can lead to carcinogenesis. Therefore, genetic variants in the AURORA pathway genes may be associated with susceptibility to pancreatic cancer. To test this hypothesis, we used three large publ...

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Vydáno v:Carcinogenesis
Hlavní autoři: Feng, Yun, Liu, Hongliang, Duan, Bensong, Liu, Zhensheng, Abbruzzese, James, Walsh, Kyle M, Zhang, Xuefeng, Wei, Qingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Biology, Genetics and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556704/
https://ncbi.nlm.nih.gov/pubmed/30794721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz029
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