Sitagliptin ameliorates advanced glycation end-product (AGE)-induced degradation of extracellular matrix in human primary chondrocytes

Accumulation of advanced glycation end-products (AGEs) increases inflammation and triggers processes involved in the pathogenesis of osteoarthritis (OA). As a major debilitating age-related disease, it is imperative that novel therapies for OA be sought. In the present study, we investigated the eff...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhu, Shijun, Gu, Ye, Wang, Wei, Bai, Jiaxiang, Ge, Gaorang, Zhang, Wenhao, Wang, Qing, Guo, Xiaobin, Xiao, Long, Tao, Yunxia, Niu, Fuwen, Nie, Zhikui, Geng, Dechun, Wang, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556674/
https://ncbi.nlm.nih.gov/pubmed/31217853
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