Tanshinone IIA induces apoptosis and autophagy in acute monocytic leukemia via downregulation of PI3K/Akt pathway

Acute myeloid leukemia (AML) is characterized by unrestrained proliferation of myeloid cells. In has been shown that tanshinone IIA (Tan IIA), exhibited anti-tumor activities on different types of cancers. However, the underlying mechanisms by which Tan IIA regulates apoptosis and autophagy in AML r...

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Detalles Bibliográficos
Publicado en:Am J Transl Res
Main Authors: Zhang, Yanping, Geng, Yan, He, Juntao, Wu, Dong, Zhang, Tong, Xue, Li, Zhang, Lei, He, Aili
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556636/
https://ncbi.nlm.nih.gov/pubmed/31217869
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