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Homoharringtonine, an approved anti-leukemia drug, suppresses triple negative breast cancer growth through a rapid reduction of anti-apoptotic protein abundance

Triple negative breast cancers (TNBC) without BRCA1/2 gene mutation or BRCAness are nowadays the breast malignancies most difficult to treat. Improvement of their treatment, for all phases of the disease, is an important unmet medical need. We analyzed the effect of homoharringtonine (HHT), a natura...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Yakhni, Mohamad, Briat, Arnaud, El Guerrab, Abderrahim, Furtado, Ludivine, Kwiatkowski, Fabrice, Miot-Noirault, Elisabeth, Cachin, Florent, Penault-Llorca, Frederique, Radosevic-Robin, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556597/
https://ncbi.nlm.nih.gov/pubmed/31218111
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