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Oleate hydratase from Staphylococcus aureus protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin

Oleate hydratases (OhyAs) belong to a large family of bacterial proteins catalyzing the hydration or isomerization of double bonds in unsaturated fatty acids. A Staphylococcus aureus gene (Sa0102) is predicted to encode an OhyA. Here, we recombinantly expressed and purified SaOhyA and found that it...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Subramanian, Chitra, Frank, Matthew W., Batte, Justin L., Whaley, Sarah G., Rock, Charles O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556589/
https://ncbi.nlm.nih.gov/pubmed/31018965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008439
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