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mTOR is key to T cell transdifferentiation

T cell transdifferentiation to functionally distinct subsets can play a key role in balancing the protective and pathogenic features of the T cell response. In a new study, Karmaus et al showed that mTORC1 activity influences metabolic heterogeneity within a T cell population to modulate transdiffer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Yan, Jiawei, Wang, Ruoning, Horng, Tiffany
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556472/
https://ncbi.nlm.nih.gov/pubmed/30726756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.008
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