Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor

Most methods for the detection of nucleic acids require many reagents and expensive and bulky instrumentation. Here, we report the development and testing of a graphene-based field-effect transistor that uses clustered regularly interspaced short palindromic repeats (CRISPR) technology to enable the...

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Udgivet i:Nat Biomed Eng
Main Authors: Hajian, Reza, Balderston, Sarah, Tran, Thanhtra, deBoer, Tara, Etienne, Jessy, Sandhu, Mandeep, Wauford, Noreen A., Chung, Jing-Yi, Nokes, Jolie, Athaiya, Mitre, Paredes, Jacobo, Peytavi, Regis, Goldsmith, Brett, Murthy, Niren, Conboy, Irina M., Aran, Kiana
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556128/
https://ncbi.nlm.nih.gov/pubmed/31097816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-019-0371-x
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