Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration

BACKGROUND: Primary brain tumors, in particular glioblastoma (GBM), remain among the most challenging cancers. Like most malignant tumors, GBM is characterized by hypoxic stress that triggers paracrine, adaptive responses, such as angiogenesis and macrophage recruitment, rescuing cancer cells from m...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Offer, Svenja, Menard, Julien A., Pérez, Julio Enríquez, de Oliveira, Kelin G., Chandran, Vineesh Indira, Johansson, Maria C., Bång-Rudenstam, Anna, Siesjö, Peter, Ebbesson, Anna, Hedenfalk, Ingrid, Sundgren, Pia C., Darabi, Anna, Belting, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556032/
https://ncbi.nlm.nih.gov/pubmed/31174567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1228-6
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