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Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
Alzheimer’s disease neuropathologic change (ADNC) is defined by progressive accumulation of β-amyloid plaques and hyperphosphorylated tau (pTau) neurofibrillary tangles across diverse regions of brain. Non-demented individuals who reach advanced age without significant ADNC are considered to be resi...
Bewaard in:
Gepubliceerd in: | Acta Neuropathol Commun |
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Hoofdauteurs: | , , , , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BioMed Central
2019
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6556006/ https://ncbi.nlm.nih.gov/pubmed/31174609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0743-1 |
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