Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins

Deterioration of biomolecules in clinical tissues is an inevitable pre-analytical process, which affects molecular measurements and thus potentially confounds conclusions from cohort analyses. Here, we investigate the degradation of mRNA and protein in 68 pairs of adjacent prostate tissue samples us...

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Publicat a:Nat Commun
Autors principals: Shao, Wenguang, Guo, Tiannan, Toussaint, Nora C., Xue, Peng, Wagner, Ulrich, Li, Li, Charmpi, Konstantina, Zhu, Yi, Wu, Jianmin, Buljan, Marija, Sun, Rui, Rutishauser, Dorothea, Hermanns, Thomas, Fankhauser, Christian Daniel, Poyet, Cedric, Ljubicic, Jelena, Rupp, Niels, Rüschoff, Jan H., Zhong, Qing, Beyer, Andreas, Ji, Jiafu, Collins, Ben C., Liu, Yansheng, Rätsch, Gunnar, Wild, Peter J., Aebersold, Ruedi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555818/
https://ncbi.nlm.nih.gov/pubmed/31175306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10513-5
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