Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice

BACKGROUND: As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would suppress inflammation via TLR4/NF-κB signaling and further promote the amelioratio...

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Detalhes bibliográficos
Publicado no:Nutr Metab (Lond)
Main Authors: Zhang, Xinsheng, Xue, Changyong, Xu, Qing, Zhang, Yong, Li, Huizi, Li, Feng, Liu, Yinghua, Guo, Changjiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555760/
https://ncbi.nlm.nih.gov/pubmed/31182969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-019-0359-2
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