M(1) muscarinic receptors modulate fear-related inputs to the prefrontal cortex: Implications for novel treatments of posttraumatic stress disorder

BACKGROUND: The prefrontal cortex (PFC) integrates information from multiple inputs to exert “top down” control allowing for appropriate responses in a given context. In psychiatric disorders such as posttraumatic stress disorder (PTSD), PFC hyperactivity is associated with inappropriate fear in saf...

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Dettagli Bibliografici
Pubblicato in:Biol Psychiatry
Autori principali: Maksymetz, James, Joffe, Max E., Moran, Sean P., Stansley, Branden J., Li, Brianna, Temple, Kayla, Engers, Darren W., Lawrence, J. Josh, Lindsley, Craig W., Conn, P. Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555658/
https://ncbi.nlm.nih.gov/pubmed/31003787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.02.020
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