Calycosin suppresses TGF-β-induced epithelial-to-mesenchymal transition and migration by upregulating BATF2 to target PAI-1 via the Wnt and PI3K/Akt signaling pathways in colorectal cancer cells

OBJECTIVES: To determine whether the upregulation of basic leucine zipper ATF-like transcription factor 2 (BATF2) by calycosin suppresses the growth and epithelial-to-mesenchymal transition (EMT) in human colorectal cancer (CRC) cells. METHOD: Cells were cultured and treated with different concentra...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Wang, Qun, Lu, Weijun, Yin, Tao, Lu, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555005/
https://ncbi.nlm.nih.gov/pubmed/31174572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1243-7
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