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Calycosin suppresses TGF-β-induced epithelial-to-mesenchymal transition and migration by upregulating BATF2 to target PAI-1 via the Wnt and PI3K/Akt signaling pathways in colorectal cancer cells
OBJECTIVES: To determine whether the upregulation of basic leucine zipper ATF-like transcription factor 2 (BATF2) by calycosin suppresses the growth and epithelial-to-mesenchymal transition (EMT) in human colorectal cancer (CRC) cells. METHOD: Cells were cultured and treated with different concentra...
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| Udgivet i: | J Exp Clin Cancer Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555005/ https://ncbi.nlm.nih.gov/pubmed/31174572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1243-7 |
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