OR31-2 Effects of Colchicine on Insulin Resistance, Pancreatic Beta-Cell Function, and Aspects of the Metabolic Syndrome (MetS) in Adults with Obesity, MetS, and Inflammation: A Pilot Randomized Controlled Trial

Introduction: Low-grade chronic inflammation, due in part to activation of the NLRP3 inflammasome, increases with increasing adiposity and plays a significant role in the development of type 2 diabetes and cardiovascular disease. However, to date, the efficacy of anti-inflammatory medications to imp...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Demidowich, Andrew, Levine, Jordan, Brady, Sheila, Broadney, Miranda, Yanovski, Jack
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
Subjects:
Diabetes Mellitus and Glucose Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554767/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR31-2
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