OR28-6 Short-Term Mifepristone Treatment Improves Hepatic and Adipose Tissue Insulin Sensitivity in Overweight and Obese Subjects with Glucose Intolerance

Background: Increased tissue cortisol availability and enhanced glucocorticoid action have been implicated in abnormal glucose and fat metabolism in patients with obesity, metabolic syndrome, and type 2 diabetes. Objective: To test the hypothesis that blockade of glucocorticoid receptor (GR) with mi...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Grewal, Shivraj, Sharma, Susmeeta, McGlotten, Raven, Muniyappa, Ranganath, Nieman, Lynnette
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Diabetes Mellitus and Glucose Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554765/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-6
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