Inhibition of the FAD containing ER oxidoreductin 1 (Ero1) protein by EN-460 a strategy for treatment of multiple myeloma

Multiple myeloma (MM) cells demonstrate high basal endoplasmic reticulum (ER) stress and are typically exquisitely sensitive to agents such as proteasome inhibitors that activate the unfolded protein response. The flavin adenosine dinucleotide (FAD) containing endoplasmic reticulum oxidoreductin enz...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Bioorg Med Chem
Hlavní autoři: Hayes, Karen, Batsomboon, Paratchata, Chen, Wei-Chih, Johnson, Brennan D., Becker, Andreas, Eschrich, Steven A., Yang, Yan, Robart, Aaron R., Dudley, Gregory, Geldenhuys, Werner J., Hazlehurst, Lori A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554731/
https://ncbi.nlm.nih.gov/pubmed/30850265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.02.016
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky