Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Anterior gradient 2 (AGR2) is a dimeric protein disulfide isomerase family member involved in the regulation of protein quality control in the endoplasmic reticulum (ER). Mouse AGR2 deletion increases intestinal inflammation and promotes the development of inflammatory bowel disease (IBD). Although...

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Pubblicato in:EMBO Mol Med
Autori principali: Maurel, Marion, Obacz, Joanna, Avril, Tony, Ding, Yong‐Ping, Papadodima, Olga, Treton, Xavier, Daniel, Fanny, Pilalis, Eleftherios, Hörberg, Johanna, Hou, Wenyang, Beauchamp, Marie‐Claude, Tourneur‐Marsille, Julien, Cazals‐Hatem, Dominique, Sommerova, Lucia, Samali, Afshin, Tavernier, Jan, Hrstka, Roman, Dupont, Aurélien, Fessart, Delphine, Delom, Frédéric, Fernandez‐Zapico, Martin E, Jansen, Gregor, Eriksson, Leif A, Thomas, David Y, Jerome‐Majewska, Loydie, Hupp, Ted, Chatziioannou, Aristotelis, Chevet, Eric, Ogier‐Denis, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554669/
https://ncbi.nlm.nih.gov/pubmed/31040128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201810120
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