Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway

Background and Aim: The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway plays a crucial role in autophagy and inflammation. Our previous studies demonstrated that Shen-Yuan-Dan Capsule (SYDC), a Chinese medicine used for treating angina pectori...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhou, Mingxue, Ren, Pan, Zhang, Ying, Li, Sinai, Li, Mengjie, Li, Ping, Shang, Juju, Liu, Weihong, Liu, Hongxu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554665/
https://ncbi.nlm.nih.gov/pubmed/31214032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00603
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