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Quantifying Protein Copy Number in Super Resolution Using an Imaging-Invariant Calibration

The use of super-resolution microscopy in recent years has revealed that proteins often form small assemblies inside cells and are organized in nanoclusters. However, determining the copy number of proteins within these nanoclusters constitutes a major challenge because of unknown labeling stoichiom...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Cella Zanacchi, Francesca, Manzo, Carlo, Magrassi, Raffaella, Derr, Nathan D., Lakadamyali, Melike
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554488/
https://ncbi.nlm.nih.gov/pubmed/31103226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.026
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