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Quantifying Protein Copy Number in Super Resolution Using an Imaging-Invariant Calibration

The use of super-resolution microscopy in recent years has revealed that proteins often form small assemblies inside cells and are organized in nanoclusters. However, determining the copy number of proteins within these nanoclusters constitutes a major challenge because of unknown labeling stoichiom...

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Foilsithe in:Biophys J
Main Authors: Cella Zanacchi, Francesca, Manzo, Carlo, Magrassi, Raffaella, Derr, Nathan D., Lakadamyali, Melike
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554488/
https://ncbi.nlm.nih.gov/pubmed/31103226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.04.026
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