Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma

Aberrant microRNA-708 (miR-708) expression is frequently reported in cancer studies; however, its role in glioma has not been examined in detail. We investigated miR-708 function in glioma and revealed that miR-708 expression was significantly down-regulated in glioma tissues and cell lines. Restora...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Chen, Yan, Deng, Xubin, Chen, Weiquan, Shi, Pengwei, Lian, Mei, Wang, Hongxiao, Wang, Kewan, Qian, Dadi, Xiao, Dong, Long, Hao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554356/
https://ncbi.nlm.nih.gov/pubmed/31171769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1671-5
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