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Oligonucleotide Therapeutics as a New Class of Drugs for Malignant Brain Tumors: Targeting mRNAs, Regulatory RNAs, Mutations, Combinations, and Beyond

Malignant brain tumors are rapidly progressive and often fatal owing to resistance to therapies and based on their complex biology, heterogeneity, and isolation from systemic circulation. Glioblastoma is the most common and most aggressive primary brain tumor, has high mortality, and affects both ch...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Krichevsky, Anna M., Uhlmann, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554258/
https://ncbi.nlm.nih.gov/pubmed/30644073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-00702-3
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