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Targeted Oligonucleotides for Treating Neurodegenerative Tandem Repeat Diseases

Nucleotide repeat disorders encompass more than 30 diseases, most of which show dominant inheritance, such as Huntington’s disease, spinocerebellar ataxias, and myotonic dystrophies. Yet others, including Friedreich’s ataxia, are recessively inherited. A common feature is the presence of a DNA tande...

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Enregistré dans:
Détails bibliographiques
Publié dans:Neurotherapeutics
Auteurs principaux: Zain, Rula, Smith, C. I. Edvard
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554256/
https://ncbi.nlm.nih.gov/pubmed/31098852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00712-9
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