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Microcircuit mechanisms through which mediodorsal thalamic input to anterior cingulate cortex exacerbates pain-related aversion.

Hyperexcitability of the anterior cingulate cortex (ACC) is thought to drive aversion associated with chronic neuropathic pain. Here we studied the contribution of input from mediodorsal thalamus (MD) to ACC, using sciatic nerve injury and chemotherapy-induced mouse models of neuropathic pain. Activ...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Meda, Karuna S., Patel, Tosha, Braz, Joao M., Malik, Ruchi, Turner, Marc L., Seifikar, Helia, Basbaum, Allan I., Sohal, Vikaas S.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554049/
https://ncbi.nlm.nih.gov/pubmed/31030955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.03.042
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