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ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma

Purpose: Ornithine decarboxylase 1 (ODC1)–an oncogene involved in the biosynthesis of polyamines–is commonly upregulated and associated with poor prognosis in numerous cancers. However, the role and mechanism of ODC1 in hepatocellular carcinoma (HCC) remains unclear. The aim of the present study was...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Onco Targets Ther
Päätekijät: Ye, Zi, Zeng, Zhirui, Shen, Yiyi, Yang, Qiang, Chen, Duidui, Chen, Zubing, Shen, Shiqiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553997/
https://ncbi.nlm.nih.gov/pubmed/31239700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S198341
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