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Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen

Hypoxia occurs in pathological conditions, such as cancer, as a result of the imbalance between oxygen supply and consumption by proliferating cells. HIFs are critical molecular mediators of the physiological response to hypoxia but also regulate multiple steps of carcinogenesis including tumor prog...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Proteomics
Hauptverfasser: Chachami, Georgia, Stankovic-Valentin, Nicolas, Karagiota, Angeliki, Basagianni, Angeliki, Plessmann, Uwe, Urlaub, Henning, Melchior, Frauke, Simos, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553927/
https://ncbi.nlm.nih.gov/pubmed/30926672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA119.001401
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